• Corpus ID: 11927098

Developmental and evolutionary implications of labial, Deformed and engrailed expression in the Drosophila head.

@article{Diederich1991DevelopmentalAE,
  title={Developmental and evolutionary implications of labial, Deformed and engrailed expression in the Drosophila head.},
  author={Robert J. Diederich and Angela M. L. Pattatucci and Thomas C. Kaufman},
  journal={Development},
  year={1991},
  volume={113 1},
  pages={
          273-81
        },
  url={https://api.semanticscholar.org/CorpusID:11927098}
}
It is suggested that distinct regulatory paradigms evolved for homeotic gene function in the development of the larval versus adult head, and that the clypeolabrum evolved from the fusion of paired labral appendages.
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41 References

Isolation, structure, and expression of labial, a homeotic gene of the Antennapedia Complex involved in Drosophila head development.

The labial (lab) gene of Drosophila melanogaster is necessary for the proper development of the embryonic and adult head and it is suggested that lab head expression provides a molecular marker for an intercalary segment that has become morphologically indistinct during the evolution of the insect head.

A genetic and developmental analysis of mutations in labial, a gene necessary for proper head formation in Drosophila melanogaster.

Novel patterns of homeotic protein accumulation in the head of the Drosophila embryo.

The authors' observations demonstrate a non-overlapping pattern in the head for those homeotic proteins required during embryogenesis, and two of the proteins, Sex combs reduced and Deformed, have different dorsal and ventral patterns of accumulation.

Developmental and molecular analysis of Deformed; a homeotic gene controlling Drosophila head development

It is shown that null mutants of Deformed result in a loss of pattern elements derived from the maxillary and mandibular segments, and a duplication of a cuticular element of the larval head skeleton, suggesting that the Xenopus gene is the frog homologue of Dfd.

A genetic and developmental analysis of mutations in the Deformed locus in Drosophila melanogaster.

Pair-rule segmentation genes regulate the expression of the homeotic selector gene, Deformed

The results support the idea that a hierarchy of homeobox regulatory genes plays a key role in dividing and determining the Drosophila body pattern.

Temporal and spatial distribution of transcripts from the Deformed gene of Drosophila

The distribution of Dfd transcripts supports the hypothesis that Dfd functions as a homeotic selector gene in the determination of posterior head segments.

Development of the eye-antenna imaginal disc and morphogenesis of the adult head in Drosophila melanogaster.

A comparison of the location of precursors in the imaginal disc with those of the differentiated structures of the adult head revealed the nature of the morphogenetic movements that must occur during evagination and differentiation.

Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein

The proboscipedia locus of the Antennapedia complex: a molecular and genetic analysis.

Notably, pb and z2 show similarities to neighboring ANT-C genes in their expression patterns, yet these similarities are not manifested in comparable loss-of-function embryonic phenotypes.