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Pia Gattinger, Christian Lupinek, Lampros Kalogiros, Mira Silar, Mihaela Zidarn, Peter Korosec, Christine Koessler, Natalija Novak, Rudolf Valenta, Irene Mittermann
The culprit insect but not severity of allergic reactions to bee and wasp venom can be determined by molecular diagnosis
www.plosone.org
www.plosone.org
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1 J
0 w
7.9999 0 0 7.9999 58.6204 649.8708 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(kU/L)Tj
3.274 0 Td
(kUA/L)Tj
3.6284 0 Td
(kUA/L)Tj
4.5709 0 Td
(Venom)Tj
5.1165 0 Td
(ISU)Tj
2.6646 0 Td
(kUA/L)Tj
4.4505 0 Td
(O.D.)Tj
4.1031 0 Td
(kUA/L)Tj
5.0812 0 Td
(ISU)Tj
3.8764 0 Td
(kUA/L)Tj
4.7055 0 Td
(kUA/L)Tj
4.5568 0 Td
(ISU)Tj
2.6716 0 Td
(kUA/L)Tj
4.3867 0 Td
(O.D.)Tj
/F6 1 Tf
-55.6728 -1.559 Td
(G1)Tj
2.9267 0 Td
(595)Tj
3.515 0 Td
(1.15)Tj
/F12 1 Tf
3.352 0 Td
(>)Tj
/F6 1 Tf
(100)Tj
4.8048 0 Td
(-1/-2)Tj
/F12 1 Tf
4.4008 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
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3.274 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7906 0 Td
(0)Tj
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3.763 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.4717 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.4788 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.7126 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
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(2.27)Tj
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(4.40)Tj
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(0.47)Tj
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(148)Tj
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(0.1)Tj
/F12 1 Tf
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(0.1)Tj
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(0.28)Tj
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(0.73)Tj
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(<)Tj
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(0.1)Tj
4.6914 0 Td
(n.d.)Tj
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(0.24)Tj
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(0.36)Tj
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3.678 0 Td
(b/w)Tj
-64.4603 -1.5591 Td
(G5)Tj
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(796)Tj
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(26.9)Tj
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(<)Tj
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(0.1)Tj
/F12 1 Tf
3.274 0 Td
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(0.1)Tj
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(0)Tj
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/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.4717 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
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/F12 1 Tf
4.5638 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0961 0 Td
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-64.8855 -1.5661 Td
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-64.4603 -1.5591 Td
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(153)Tj
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(0.14)Tj
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(<)Tj
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(<)Tj
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(0.1)Tj
/F12 1 Tf
4.7126 0 Td
(<)Tj
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(0.1)Tj
4.0961 0 Td
(1.47)Tj
3.2741 0 Td
(2.01)Tj
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(0)Tj
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3.678 0 Td
(b/w)Tj
-64.4603 -1.5661 Td
(G8)Tj
2.8062 0 Td
(65.8)Tj
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-64.8855 -1.5591 Td
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(n.d.)Tj
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(<)Tj
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(n.d.)Tj
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/F12 1 Tf
3.7985 0 Td
(<)Tj
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(0.1)Tj
/F12 1 Tf
3.274 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7339 0 Td
(0)Tj
4.3371 0 Td
(2)Tj
4.1882 0 Td
(b)Tj
-65.2114 -1.5662 Td
(G10)Tj
3.1676 0 Td
(124)Tj
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(59.9)Tj
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(-3/-2)Tj
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(b/w)Tj
-64.7012 -1.559 Td
(G11)Tj
3.0471 0 Td
(12.2)Tj
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(0.1)Tj
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(0.1)Tj
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(<)Tj
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(0.1)Tj
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(0.1)Tj
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(0.96)Tj
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(0)Tj
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-65.1264 -1.5591 Td
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(189)Tj
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(b/w)Tj
-64.7012 -1.5591 Td
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(18.3)Tj
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(t-IgE)Tj
-0.3473 -1.1906 Td
(CAP)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 73.4173 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(a\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 90.4818 678.5007 cm
BT
/F11 1 Tf
1 TL
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(bee)Tj
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(CAP)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 102.274 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(b\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 116.7307 678.5007 cm
BT
/F11 1 Tf
1 TL
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(wasp)Tj
-0.3543 -1.1905 Td
(CAP)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 131.5842 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(c\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 148.3086 678.5007 cm
BT
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1 TL
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(test)Tj
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ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 177.7322 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(d\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 197.0645 678.5007 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(rApi)Tj
2.1826 0 Td
(m)Tj
1.0772 0 Td
(1)Tj
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(Chip)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 207.0992 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(e\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 213.6755 668.9763 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(CAP)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 231.3637 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(f\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 241.3417 678.5007 cm
BT
/F11 1 Tf
1 TL
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(rApi)Tj
2.1826 0 Td
(m)Tj
1.0701 0 Td
(2)Tj
-3.1606 -1.1905 Td
(ELISA)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 265.6062 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(g\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 277.3417 678.5007 cm
BT
/F11 1 Tf
1 TL
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(rApi)Tj
2.1756 0 Td
(m)Tj
1.0771 0 Td
(3)Tj
-2.8275 -1.1905 Td
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ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 298.4881 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(h\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 313.1149 678.5007 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(rApi)Tj
2.1826 0 Td
(m)Tj
1.0772 0 Td
(4)Tj
-2.7709 -1.1905 Td
(Chip)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 335.3952 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(i\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 348.9448 678.5007 cm
BT
/F11 1 Tf
1 TL
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(rApi)Tj
2.1826 0 Td
(m)Tj
1.0701 0 Td
(5)Tj
-2.7212 -1.1905 Td
(CAP)Tj
ET
Q
q
1 j
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0 w
5.9998 0 0 5.3325 370.885 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(j\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 384.6614 678.5007 cm
BT
/F11 1 Tf
1 TL
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(rApi)Tj
2.1826 0 Td
(m)Tj
1.0701 0 Td
(10)Tj
-2.5583 -1.1905 Td
(CAP)Tj
ET
Q
q
1 j
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0 w
5.9998 0 0 5.3325 407.9055 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(k\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 423.7228 678.5007 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(rVes)Tj
2.1614 0 Td
(v)Tj
0.6945 0 Td
(5)Tj
-2.8559 -1.1905 Td
(Chip)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 442.0913 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(l\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 423.7228 659.5086 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(CAP)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 441.411 663.0803 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(m\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 477.9779 678.5007 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(rVes)Tj
2.1614 0 Td
(v)Tj
0.7016 0 Td
(1)Tj
-2.9976 -1.1905 Td
(ELISA)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 500.4283 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(n\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 513.0141 678.5007 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(Mueller)Tj
-0.0992 -1.1905 Td
(Grade)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 534.7275 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(o\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 548.3338 678.5007 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(culprit)Tj
-0.248 -1.1905 Td
(insect)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 567.6661 672.548 cm
BT
/F11 1 Tf
1 TL
0 0 Td
(p\))Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 58.6204 646.9795 cm
BT
/F11 1 Tf
1 TL
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(kU/L)Tj
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(kUA/L)Tj
3.6284 0 Td
(kUA/L)Tj
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(Venom)Tj
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(ISU)Tj
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(kUA/L)Tj
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(O.D.)Tj
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(kUA/L)Tj
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(kUA/L)Tj
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(9.07)Tj
4.5355 0 Td
(-3/-3)Tj
4.5425 0 Td
(3.52)Tj
3.2741 0 Td
(2.91)Tj
4.0535 0 Td
(0.11)Tj
4.5001 0 Td
(0.21)Tj
/F12 1 Tf
4.3299 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.4788 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
5.0953 0 Td
(0.6)Tj
3.7134 0 Td
(3.06)Tj
3.2741 0 Td
(5.04)Tj
4.585 0 Td
(0)Tj
4.3371 0 Td
(2)Tj
3.678 0 Td
(b/w)Tj
-64.7012 -1.5662 Td
(G59)Tj
3.1676 0 Td
(162)Tj
3.515 0 Td
(0.37)Tj
3.6213 0 Td
(27.2)Tj
4.2307 0 Td
(neg/-1)Tj
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4.7056 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.274 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7906 0 Td
(0)Tj
/F12 1 Tf
3.763 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.4717 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.6276 0 Td
(3.34)Tj
/F12 1 Tf
4.5638 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0961 0 Td
(8.07)Tj
3.2741 0 Td
(7.95)Tj
3.9968 0 Td
(0.16)Tj
4.9253 0 Td
(4)Tj
4.1032 0 Td
(w)Tj
-65.1264 -1.559 Td
(G60)Tj
3.1676 0 Td
(562)Tj
3.515 0 Td
(3.37)Tj
3.6213 0 Td
(11.2)Tj
4.2307 0 Td
(neg/-1)Tj
4.8473 0 Td
(2.15)Tj
3.515 0 Td
(0.5)Tj
3.8126 0 Td
(0.14)Tj
4.5638 0 Td
(n.d.)Tj
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4.2662 0 Td
(<)Tj
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(0.1)Tj
4.6914 0 Td
(n.d.)Tj
4.6488 0 Td
(0.36)Tj
3.9473 0 Td
(8.98)Tj
3.2741 0 Td
(6.88)Tj
4.2378 0 Td
(0.4)Tj
4.6843 0 Td
(3)Tj
3.678 0 Td
(b/w)Tj
-64.7012 -1.5662 Td
(G61)Tj
3.0471 0 Td
(25.8)Tj
3.6355 0 Td
(30.5)Tj
3.8622 0 Td
(0.6)Tj
3.9898 0 Td
(-2/neg)Tj
4.8473 0 Td
(5.71)Tj
3.2741 0 Td
(6.12)Tj
4.0535 0 Td
(0.39)Tj
/F12 1 Tf
4.3583 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.4717 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.6276 0 Td
(0.76)Tj
4.7126 0 Td
(2.87)Tj
/F12 1 Tf
3.7985 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.274 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.1457 0 Td
(0.24)Tj
4.9253 0 Td
(2)Tj
3.678 0 Td
(b/w)Tj
-64.7012 -1.5591 Td
(G62)Tj
3.1676 0 Td
(146)Tj
3.7489 0 Td
(0.4)Tj
3.3874 0 Td
(16.6)Tj
4.7126 0 Td
(0/-3)Tj
/F12 1 Tf
4.2237 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.274 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7906 0 Td
(0)Tj
/F12 1 Tf
3.763 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.4717 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.6276 0 Td
(0.23)Tj
/F12 1 Tf
4.5638 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0961 0 Td
(4.26)Tj
3.2741 0 Td
(1.98)Tj
3.9968 0 Td
(0.53)Tj
4.9253 0 Td
(2)Tj
4.1032 0 Td
(w)Tj
-65.1264 -1.5661 Td
(G63)Tj
3.0471 0 Td
(50.1)Tj
3.6355 0 Td
(0.64)Tj
3.6213 0 Td
(7.72)Tj
4.7126 0 Td
(0/-2)Tj
4.3654 0 Td
(0.18)Tj
/F12 1 Tf
3.1323 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7906 0 Td
(0)Tj
4.1457 0 Td
(0.2)Tj
/F12 1 Tf
4.089 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8686 0 Td
(0.4)Tj
/F12 1 Tf
4.3228 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0961 0 Td
(2.24)Tj
3.2741 0 Td
(3.97)Tj
4.585 0 Td
(0)Tj
4.3371 0 Td
(3)Tj
3.678 0 Td
(b/w)Tj
-64.7012 -1.5591 Td
(G64)Tj
3.1676 0 Td
(600)Tj
3.515 0 Td
(15.6)Tj
3.8622 0 Td
(0.6)Tj
3.9898 0 Td
(-2/neg)Tj
4.8473 0 Td
(1.52)Tj
3.2741 0 Td
(3.34)Tj
4.0535 0 Td
(0.38)Tj
4.5001 0 Td
(0.99)Tj
/F12 1 Tf
4.3299 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.6276 0 Td
(0.22)Tj
4.9465 0 Td
(5.7)Tj
/F12 1 Tf
3.5646 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.274 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7339 0 Td
(0)Tj
4.3371 0 Td
(2)Tj
4.1882 0 Td
(b)Tj
-65.2114 -1.5661 Td
(G65)Tj
2.9267 0 Td
(3301)Tj
3.7559 0 Td
(4.96)Tj
/F12 1 Tf
3.352 0 Td
(>)Tj
/F6 1 Tf
(100)Tj
4.9819 0 Td
(0/-2)Tj
4.3654 0 Td
(1.93)Tj
3.2741 0 Td
(1.21)Tj
4.6488 0 Td
(0)Tj
3.9685 0 Td
(n.d.)Tj
/F12 1 Tf
4.2662 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.6914 0 Td
(n.d.)Tj
/F12 1 Tf
4.5 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
3.8552 0 Td
(186.8)Tj
3.274 0 Td
(184.1)Tj
4.2378 0 Td
(0.21)Tj
4.9253 0 Td
(2)Tj
3.678 0 Td
(b/w)Tj
-64.7012 -1.5591 Td
(G66)Tj
3.0471 0 Td
(61.5)Tj
3.6355 0 Td
(1.96)Tj
3.6213 0 Td
(3.37)Tj
4.2307 0 Td
(neg/-3)Tj
4.8473 0 Td
(4.43)Tj
3.2741 0 Td
(1.04)Tj
4.6488 0 Td
(0)Tj
3.9048 0 Td
(0.15)Tj
/F12 1 Tf
4.3299 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.6276 0 Td
(0.16)Tj
4.7126 0 Td
(0.74)Tj
3.9473 0 Td
(3.37)Tj
3.2741 0 Td
(1.98)Tj
3.9968 0 Td
(0.27)Tj
4.9253 0 Td
(2)Tj
3.678 0 Td
(b/w)Tj
-64.7012 -1.5662 Td
(G67)Tj
3.1676 0 Td
(426)Tj
3.515 0 Td
(63.1)Tj
3.6213 0 Td
(31.9)Tj
4.5355 0 Td
(-2/-3)Tj
4.5425 0 Td
(9.26)Tj
3.515 0 Td
(9.4)Tj
4.4079 0 Td
(0)Tj
3.9685 0 Td
(n.d.)Tj
/F12 1 Tf
4.2662 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.6914 0 Td
(n.d.)Tj
/F12 1 Tf
4.5 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0961 0 Td
(7.99)Tj
3.2741 0 Td
(5.42)Tj
4.585 0 Td
(0)Tj
4.3371 0 Td
(4)Tj
3.678 0 Td
(b/w)Tj
-64.7012 -2.3456 Td
(a)Tj
0.6661 0 Td
(total)Tj
2.0268 0 Td
(IgE,)Tj
1.8424 0 Td
(ImmunoC)Tj
4.2308 0 Td
(AP)Tj
-8.7661 -1.4953 Td
(b)Tj
0.737 0 Td
(bee)Tj
1.5945 0 Td
(venom)Tj
2.9905 0 Td
(sIgE,)Tj
2.2039 0 Td
(ImmunoCA)Tj
4.9182 0 Td
(P)Tj
-12.4441 -1.5024 Td
(c)Tj
0.659 0 Td
(wasp)Tj
2.2322 0 Td
(venom)Tj
2.9906 0 Td
(sIgE,)Tj
2.204 0 Td
(ImmunoCA)Tj
4.9181 0 Td
(P)Tj
-13.0039 -1.5024 Td
(d)Tj
0.7582 0 Td
(intradermal)Tj
4.996 0 Td
(skin)Tj
1.9134 0 Td
(test;)Tj
1.8497 0 Td
(given)Tj
2.4023 0 Td
(is)Tj
0.8646 0 Td
(the)Tj
1.4811 0 Td
(threshold)Tj
4.0465 0 Td
(concent)Tj
3.1819 0 Td
(ration)Tj
2.6717 0 Td
(of)Tj
1.0276 0 Td
(a)Tj
0.6661 0 Td
(positive)Tj
3.352 0 Td
(skin)Tj
1.9063 0 Td
(reaction,)Tj
3.756 0 Td
(-4:)Tj
1.2827 0 Td
(0.0001)Tj
/F13 1 Tf
2.8488 0 Td
[()]TJ
/F6 1 Tf
(g/ml,)Tj
2.8347 0 Td
(-3:)Tj
1.2897 0 Td
(0.001)Tj
/F13 1 Tf
2.3741 0 Td
[()]TJ
/F6 1 Tf
(g/ml,)Tj
2.8346 0 Td
(-2:)Tj
1.2898 0 Td
(0.01)Tj
/F13 1 Tf
1.8922 0 Td
[()]TJ
/F6 1 Tf
(g/ml,)Tj
2.8346 0 Td
(-1:)Tj
1.2898 0 Td
(0.1)Tj
/F13 1 Tf
1.4102 0 Td
[()]TJ
/F6 1 Tf
(g/ml,)Tj
2.8347 0 Td
(0:)Tj
0.9425 0 Td
(1)Tj
/F13 1 Tf
0.7016 0 Td
[()]TJ
/F6 1 Tf
(g/ml)Tj
2.6079 0 Td
(venom,)Tj
-64.1413 -1.4953 Td
(neg:)Tj
1.8992 0 Td
(no)Tj
1.2897 0 Td
(reaction)Tj
-3.1889 -1.5023 Td
(e)Tj
0.659 0 Td
(IgE-react)Tj
3.6921 0 Td
(ivity)Tj
1.9843 0 Td
(to)Tj
1.0417 0 Td
(non-glyco)Tj
4.0677 0 Td
(sylated)Tj
2.9977 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0488 0 Td
(1)Tj
0.7087 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1977 0 Td
(allergen)Tj
3.4087 0 Td
(micro-ar)Tj
3.5575 0 Td
(ray)Tj
-30.5718 -1.5024 Td
(f)Tj
0.5173 0 Td
(IgE-reactivit)Tj
4.996 0 Td
(y)Tj
0.6874 0 Td
(to)Tj
1.0417 0 Td
(non-glyco)Tj
4.0678 0 Td
(sylated)Tj
2.9977 0 Td
(rApi)Tj
2.0763 0 Td
(m)Tj
1.0489 0 Td
(1)Tj
0.7086 0 Td
(measured)Tj
4.1316 0 Td
(by)Tj
1.1976 0 Td
(ImmunoCAP)Tj
-23.4709 -1.4953 Td
(g)Tj
0.6945 0 Td
(IgE-reactivit)Tj
4.996 0 Td
(y)Tj
0.6874 0 Td
(to)Tj
1.0417 0 Td
(non-glyc)Tj
3.5575 0 Td
(osylated)Tj
3.5008 0 Td
(rApi)Tj
2.0835 0 Td
(m)Tj
1.0488 0 Td
(2)Tj
0.7087 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1977 0 Td
(ELISA)Tj
-23.6481 -1.5024 Td
(h)Tj
0.7582 0 Td
(IgE-reactiv)Tj
4.422 0 Td
(ity)Tj
1.2615 0 Td
(to)Tj
1.0417 0 Td
(non-glyc)Tj
3.5575 0 Td
(osylated)Tj
3.5008 0 Td
(rApi)Tj
2.0835 0 Td
(m)Tj
1.0488 0 Td
(3)Tj
0.7087 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1977 0 Td
(ImmunoCA)Tj
4.9181 0 Td
(P)Tj
-28.63 -1.5023 Td
(i)Tj
0.5031 0 Td
(IgE-react)Tj
3.6921 0 Td
(ivity)Tj
1.9842 0 Td
(to)Tj
1.0418 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0488 0 Td
(4)Tj
0.7087 0 Td
(measured)Tj
4.1386 0 Td
(by)Tj
1.1905 0 Td
(allergen)Tj
3.4087 0 Td
(micro-array)Tj
-19.7929 -1.4953 Td
(j)Tj
0.4889 0 Td
(IgE-reactiv)Tj
4.422 0 Td
(ity)Tj
1.2615 0 Td
(to)Tj
1.0417 0 Td
(non-glyc)Tj
3.5575 0 Td
(osylated)Tj
3.5008 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0559 0 Td
(5)Tj
0.7016 0 Td
(measured)Tj
4.1386 0 Td
(by)Tj
1.1977 0 Td
(ImmunoC)Tj
4.2307 0 Td
(AP)Tj
-27.6733 -1.5024 Td
(k)Tj
0.7299 0 Td
(IgE-react)Tj
3.6921 0 Td
(ivity)Tj
1.9913 0 Td
(to)Tj
1.0347 0 Td
(non-glycosy)Tj
4.8898 0 Td
(lated)Tj
2.1756 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0488 0 Td
(10)Tj
1.1906 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1976 0 Td
(ImmunoCA)Tj
4.9182 0 Td
(P)Tj
-29.0765 -1.5024 Td
(l)Tj
0.4819 0 Td
(IgE-react)Tj
3.692 0 Td
(ivity)Tj
1.9843 0 Td
(to)Tj
1.0417 0 Td
(rVes)Tj
2.0906 0 Td
(v)Tj
0.6874 0 Td
(5)Tj
0.7087 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1976 0 Td
(allergen)Tj
3.4087 0 Td
(micro-a)Tj
3.1819 0 Td
(rray)Tj
-22.6063 -1.4953 Td
(m)Tj
1.0488 0 Td
(IgE-reactiv)Tj
4.422 0 Td
(ity)Tj
1.2614 0 Td
(to)Tj
1.0417 0 Td
(rVes)Tj
2.0835 0 Td
(v)Tj
0.6874 0 Td
(5)Tj
0.7087 0 Td
(measured)Tj
4.1386 0 Td
(by)Tj
1.1906 0 Td
(ImmunoCAP)Tj
-16.5827 -1.5023 Td
(n)Tj
0.7795 0 Td
(IgE-reactiv)Tj
4.422 0 Td
(ity)Tj
1.2614 0 Td
(to)Tj
1.0418 0 Td
(rVes)Tj
2.0834 0 Td
(v)Tj
0.6874 0 Td
(1)Tj
0.7087 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1977 0 Td
(ELISA)Tj
-16.3134 -1.5024 Td
(o)Tj
0.737 0 Td
(clinical)Tj
3.1109 0 Td
(severity)Tj
3.3024 0 Td
(in)Tj
1.0488 0 Td
(Mueller)Tj
3.3733 0 Td
(grade)Tj
2.4662 0 Td
(or)Tj
1.1126 0 Td
(large)Tj
2.1827 0 Td
(local)Tj
2.0976 0 Td
(reaction)Tj
-19.4315 -1.4953 Td
(p)Tj
0.7512 0 Td
(accordin)Tj
3.5148 0 Td
(g)Tj
0.7016 0 Td
(to)Tj
1.0418 0 Td
(compone)Tj
3.7559 0 Td
(nt-resolved)Tj
4.7693 0 Td
(diagnosis)Tj
-14.5346 -1.5024 Td
(Abbr:)Tj
2.537 0 Td
(n.d.:)Tj
1.9913 0 Td
(not)Tj
1.5945 0 Td
(done,)Tj
2.4732 0 Td
(O.D.:)Tj
2.3953 0 Td
(optical)Tj
2.941 0 Td
(density,)Tj
3.359 0 Td
(LLR:)Tj
2.1615 0 Td
(large)Tj
2.1827 0 Td
(local)Tj
2.0976 0 Td
(reaction,)Tj
3.7489 0 Td
(b:)Tj
0.9708 0 Td
(bee,)Tj
1.8142 0 Td
(w:)Tj
1.1481 0 Td
(wasp,)Tj
2.4591 0 Td
(b/w:)Tj
1.9842 0 Td
(bee)Tj
1.5945 0 Td
(and)Tj
1.7433 0 Td
(wasp)Tj
-39.1962 -1.4953 Td
(IgE-levels)Tj
/F14 1 Tf
4.1314 0 Td
()Tj
/F6 1 Tf
0.9992 0 Td
(0.1)Tj
1.4174 0 Td
(ISU,)Tj
/F14 1 Tf
2.0126 0 Td
()Tj
/F6 1 Tf
0.9992 0 Td
(0.35)Tj
1.8921 0 Td
(kU)Tj
ET
Q
q
1 j
1 J
0 w
5.9998 0 0 5.3325 137.4803 123.4204 cm
BT
/F6 1 Tf
1 TL
0 0 Td
(A)Tj
ET
Q
q
1 j
1 J
0 w
7.9999 0 0 7.9999 141.6188 124.7811 cm
BT
/F6 1 Tf
1 TL
0 0 Td
(/L)Tj
1.1055 0 Td
(are)Tj
1.4598 0 Td
(highlighted)Tj
4.8048 0 Td
(in)Tj
1.0488 0 Td
(grey)Tj
0.83 0.64 0.02 0 k
/F8 1 Tf
-0.025 Tc
-21.6213 -2.2535 Td
(https://do)Tj
3.5575 0 Td
(i.org/10.1371/j)Tj
5.4426 0 Td
(ournal.pone)Tj
4.4078 0 Td
(.0199250.t001)Tj
ET
Q
q
1 j
1 J
0 w
576 737.1 m
36 737.1 l
36 737.6 l
576 737.6 l
f*
36 741.2598 107.1496 23.6976 re
W* n
q
107.0929 0 0 23.6409 36 741.3165 cm
q
/I0 Do
Q
Q
Q
q
0 0 612 792 re
W* n
1 j
1 J
0 w
7.9999 0 0 7.9999 426.2173 745.7952 cm
BT
/F0 1 Tf
1 TL
-0.005 Tc
0 0 Td
(Molecular)Tj
4.4716 0 Td
(diagnosis)Tj
4.3583 0 Td
(of)Tj
1.0418 0 Td
(insect)Tj
2.785 0 Td
(venom)Tj
3.1749 0 Td
(allergy)Tj
ET
Q
q
1 j
1 J
0 w
36 48.0002 m
576 48.0002 l
576 47.5002 l
36 47.5002 l
f*
0.83 0.64 0.02 0 k
81.5811 34.9228 m
237.8835 34.9228 l
h
f*
0 g
7.9999 0 0 7.9999 36 36 cm
BT
/F0 1 Tf
1 TL
-0.005 Tc
0 0 Td
(PLOS)Tj
2.8559 0 Td
(ONE)Tj
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4.3442 0 Td
(neg/neg)Tj
5.0953 0 Td
(0.29)Tj
3.189 0 Td
(0.69)Tj
4.663 0 Td
(0)Tj
/F12 1 Tf
3.7914 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.7551 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.8835 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.189 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7481 0 Td
(0)Tj
3.0402 0 Td
(0)Tj
0.7086 0 Td
(\(LLR\))Tj
4.7977 0 Td
(b)Tj
-65.0909 -1.5662 Td
(S10)Tj
2.9975 0 Td
(n.d.)Tj
3.5859 0 Td
(10.7)Tj
/F12 1 Tf
3.2598 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.3442 0 Td
(neg/neg)Tj
/F12 1 Tf
4.9536 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.2236 0 Td
(0.69)Tj
/F12 1 Tf
4.3796 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.7551 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.8835 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.189 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7481 0 Td
(0)Tj
4.3512 0 Td
(1)Tj
4.1953 0 Td
(b)Tj
-65.0909 -1.559 Td
(S11)Tj
2.9337 0 Td
(57.1)Tj
3.6497 0 Td
(10.9)Tj
/F12 1 Tf
3.2598 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.5922 0 Td
(10/neg)Tj
4.8473 0 Td
(0.92)Tj
3.189 0 Td
(2.63)Tj
4.663 0 Td
(0)Tj
4.004 0 Td
(n.d.)Tj
4.4504 0 Td
(0.32)Tj
4.5851 0 Td
(n.d.)Tj
4.6984 0 Td
(16.1)Tj
/F12 1 Tf
3.7347 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.189 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7481 0 Td
(0)Tj
4.3512 0 Td
(2)Tj
4.1953 0 Td
(b)Tj
-65.0909 -1.5591 Td
(S12)Tj
3.0471 0 Td
(189)Tj
/F12 1 Tf
3.1536 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.2662 0 Td
(2.3)Tj
3.7346 0 Td
(100/100)Tj
/F12 1 Tf
4.9395 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8118 0 Td
(0)Tj
/F12 1 Tf
3.7914 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.7551 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0323 0 Td
(1.11)Tj
3.182 0 Td
(1.24)Tj
4.6063 0 Td
(0)Tj
4.3512 0 Td
(4)Tj
4.1103 0 Td
(w)Tj
-65.0059 -1.5661 Td
(S13)Tj
3.0471 0 Td
(224)Tj
/F12 1 Tf
3.1536 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.0323 0 Td
(1.96)Tj
4.2024 0 Td
(neg/10)Tj
/F12 1 Tf
4.7056 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8118 0 Td
(0)Tj
/F12 1 Tf
3.7914 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.663 0 Td
(0.28)Tj
/F12 1 Tf
4.6134 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0323 0 Td
(2.35)Tj
3.182 0 Td
(1.53)Tj
4.0181 0 Td
(0.58)Tj
4.9394 0 Td
(3)Tj
4.1103 0 Td
(w)Tj
-65.0059 -1.5591 Td
(S14)Tj
2.9337 0 Td
(84.7)Tj
/F12 1 Tf
3.267 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.0323 0 Td
(11.2)Tj
4.2024 0 Td
(neg/10)Tj
/F12 1 Tf
4.7056 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8118 0 Td
(0)Tj
/F12 1 Tf
3.7914 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.7551 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0323 0 Td
(0.73)Tj
3.182 0 Td
(0.69)Tj
4.0181 0 Td
(0.29)Tj
4.9394 0 Td
(3)Tj
4.1103 0 Td
(w)Tj
-65.0059 -1.5662 Td
(S15)Tj
3.0471 0 Td
(638)Tj
/F12 1 Tf
3.1536 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.0323 0 Td
(4.67)Tj
4.2024 0 Td
(neg/10)Tj
/F12 1 Tf
4.7056 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8118 0 Td
(0)Tj
4.004 0 Td
(n.d.)Tj
/F12 1 Tf
4.3087 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.7268 0 Td
(n.d.)Tj
/F12 1 Tf
4.5496 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0323 0 Td
(1.09)Tj
3.182 0 Td
(1.43)Tj
4.0181 0 Td
(0.37)Tj
4.9394 0 Td
(2)Tj
4.1103 0 Td
(w)Tj
-65.0059 -1.559 Td
(S16)Tj
3.0471 0 Td
(435)Tj
/F12 1 Tf
3.1536 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.0323 0 Td
(9.05)Tj
3.9615 0 Td
(neg/100)Tj
/F12 1 Tf
4.9465 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8118 0 Td
(0)Tj
/F12 1 Tf
3.7914 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.7551 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0323 0 Td
(2.38)Tj
3.182 0 Td
(2.66)Tj
4.6063 0 Td
(0)Tj
4.3512 0 Td
(2)Tj
4.1103 0 Td
(w)Tj
-65.0059 -1.5662 Td
(S17)Tj
3.2881 0 Td
(96)Tj
/F12 1 Tf
2.9126 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.0323 0 Td
(1.94)Tj
4.2024 0 Td
(neg/10)Tj
/F12 1 Tf
4.7056 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8118 0 Td
(0)Tj
/F12 1 Tf
3.7914 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.7551 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0323 0 Td
(0.67)Tj
3.182 0 Td
(0.58)Tj
4.0181 0 Td
(0.28)Tj
4.9394 0 Td
(3)Tj
4.1103 0 Td
(w)Tj
-65.0059 -1.5591 Td
(S18)Tj
2.9337 0 Td
(61.6)Tj
/F12 1 Tf
3.267 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.0323 0 Td
(3.57)Tj
4.2024 0 Td
(neg/10)Tj
/F12 1 Tf
4.7056 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8118 0 Td
(0)Tj
/F12 1 Tf
3.7914 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.7551 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0323 0 Td
(2.39)Tj
3.182 0 Td
(2.02)Tj
4.0181 0 Td
(0.41)Tj
4.9394 0 Td
(4)Tj
4.1103 0 Td
(w)Tj
-65.0059 -1.5661 Td
(S19)Tj
3.0471 0 Td
(171)Tj
/F12 1 Tf
3.1536 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.0323 0 Td
(8.19)Tj
3.9615 0 Td
(neg/100)Tj
/F12 1 Tf
4.9465 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8118 0 Td
(0)Tj
/F12 1 Tf
3.7914 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.663 0 Td
(0.43)Tj
/F12 1 Tf
4.6134 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0323 0 Td
(3.44)Tj
3.182 0 Td
(3.16)Tj
4.6063 0 Td
(0)Tj
4.3512 0 Td
(2)Tj
4.1103 0 Td
(w)Tj
-65.0059 -1.5591 Td
(S20)Tj
2.9337 0 Td
(61.5)Tj
/F12 1 Tf
3.267 0 Td
(<)Tj
/F6 1 Tf
(0.35)Tj
4.0323 0 Td
(4.93)Tj
4.2024 0 Td
(neg/10)Tj
/F12 1 Tf
4.7056 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
3.1819 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.8118 0 Td
(0)Tj
/F12 1 Tf
3.7914 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.5213 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
/F12 1 Tf
4.7551 0 Td
(<)Tj
/F6 1 Tf
(0.1)Tj
4.0323 0 Td
(3.41)Tj
3.182 0 Td
(5.29)Tj
4.6063 0 Td
(0)Tj
4.3512 0 Td
(4)Tj
4.1103 0 Td
(w)Tj
-65.1193 -2.3457 Td
(a\))Tj
1.0063 0 Td
(total)Tj
2.0267 0 Td
(IgE,)Tj
1.8425 0 Td
(ImmunoCA)Tj
4.9181 0 Td
(P)Tj
-9.7936 -1.5023 Td
(b\))Tj
1.0842 0 Td
(bee)Tj
1.5874 0 Td
(venom)Tj
2.9905 0 Td
(sIgE,)Tj
2.204 0 Td
(ImmunoCAP)Tj
-7.8661 -1.4953 Td
(c\))Tj
0.9992 0 Td
(wasp)Tj
2.2322 0 Td
(venom)Tj
2.9906 0 Td
(sIgE,)Tj
2.2039 0 Td
(ImmunoCAP)Tj
-8.4259 -1.5024 Td
(d\))Tj
1.1055 0 Td
(skin)Tj
1.9062 0 Td
(prick)Tj
2.3173 0 Td
(test;)Tj
1.8497 0 Td
(given)Tj
2.4023 0 Td
(is)Tj
0.8646 0 Td
(the)Tj
1.4882 0 Td
(threshold)Tj
4.0394 0 Td
(concentr)Tj
3.5575 0 Td
(ation)Tj
2.3032 0 Td
(of)Tj
1.0276 0 Td
(a)Tj
0.6661 0 Td
(positive)Tj
3.3449 0 Td
(skin)Tj
1.9134 0 Td
(reactio)Tj
2.7355 0 Td
(n)Tj
-31.5214 -1.5024 Td
(10)Tj
/F13 1 Tf
1.1834 0 Td
[()]TJ
/F6 1 Tf
(g/ml,)Tj
2.8346 0 Td
(100)Tj
/F13 1 Tf
1.6654 0 Td
[()]TJ
/F6 1 Tf
(g/ml,)Tj
2.8346 0 Td
(neg:)Tj
1.9064 0 Td
(no)Tj
1.2897 0 Td
(reactio)Tj
2.7355 0 Td
(n)Tj
-14.4496 -1.4953 Td
(e\))Tj
0.9992 0 Td
(IgE-reactiv)Tj
4.422 0 Td
(ity)Tj
1.2614 0 Td
(to)Tj
1.0347 0 Td
(non-glycosy)Tj
4.8898 0 Td
(lated)Tj
2.1756 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0488 0 Td
(1)Tj
0.7087 0 Td
(measured)Tj
4.1386 0 Td
(by)Tj
1.1905 0 Td
(allergen)Tj
3.4087 0 Td
(micro-array)Tj
-27.3544 -1.5023 Td
(f\))Tj
0.8645 0 Td
(IgE-react)Tj
3.6921 0 Td
(ivity)Tj
1.9914 0 Td
(to)Tj
1.0346 0 Td
(non-glycosy)Tj
4.8898 0 Td
(lated)Tj
2.1756 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0488 0 Td
(1)Tj
0.7087 0 Td
(measured)Tj
4.1386 0 Td
(by)Tj
1.1906 0 Td
(ImmunoCAP)Tj
-23.8111 -1.5024 Td
(g\))Tj
1.0417 0 Td
(IgE-react)Tj
3.6921 0 Td
(ivity)Tj
1.9842 0 Td
(to)Tj
1.0418 0 Td
(non-glycosy)Tj
4.8898 0 Td
(lated)Tj
2.1756 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0488 0 Td
(2)Tj
0.7087 0 Td
(measured)Tj
4.1386 0 Td
(by)Tj
1.1905 0 Td
(ELISA)Tj
-23.9882 -1.4953 Td
(h\))Tj
1.1055 0 Td
(IgE-react)Tj
3.692 0 Td
(ivity)Tj
1.9843 0 Td
(to)Tj
1.0418 0 Td
(non-glyco)Tj
4.0677 0 Td
(sylated)Tj
2.9977 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0488 0 Td
(3)Tj
0.7087 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1976 0 Td
(ImmunoCAP)Tj
-24.052 -1.5024 Td
(i\))Tj
0.8433 0 Td
(IgE-reactiv)Tj
4.422 0 Td
(ity)Tj
1.2614 0 Td
(to)Tj
1.0346 0 Td
(rApi)Tj
2.0835 0 Td
(m)Tj
1.0489 0 Td
(4)Tj
0.7086 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1977 0 Td
(allergen)Tj
3.4087 0 Td
(micro-a)Tj
3.1819 0 Td
(rray)Tj
-23.3221 -1.5023 Td
(j\))Tj
0.8291 0 Td
(IgE-reactivit)Tj
4.996 0 Td
(y)Tj
0.6874 0 Td
(to)Tj
1.0418 0 Td
(non-glyc)Tj
3.5575 0 Td
(osylated)Tj
3.5079 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0488 0 Td
(5)Tj
0.7087 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1976 0 Td
(ImmunoCA)Tj
4.9182 0 Td
(P)Tj
-28.7009 -1.4953 Td
(k\))Tj
1.0701 0 Td
(IgE-reactiv)Tj
4.4219 0 Td
(ity)Tj
1.2615 0 Td
(to)Tj
1.0417 0 Td
(non-glyc)Tj
3.5575 0 Td
(osylated)Tj
3.5008 0 Td
(rApi)Tj
2.0764 0 Td
(m)Tj
1.0559 0 Td
(10)Tj
1.1835 0 Td
(measured)Tj
4.1315 0 Td
(by)Tj
1.1977 0 Td
(ImmunoCAP)Tj
-24.4985 -1.5024 Td
(l\))Tj
0.822 0 Td
(IgE-reactiv)Tj
4.422 0 Td
(ity)Tj
1.2614 0 Td
(to)Tj
1.0347 0 Td
(rVes)Tj
2.0906 0 Td
(v)Tj
0.6874 0 Td
(5)Tj
0.7086 0 Td
(measured)Tj
4.1316 0 Td
(by)Tj
1.1976 0 Td
(allergen)Tj
3.4087 0 Td
(micro-ar)Tj
3.5575 0 Td
(ray)Tj
-23.3221 -1.5024 Td
(m\))Tj
1.396 0 Td
(IgE-react)Tj
3.6921 0 Td
(ivity)Tj
1.9843 0 Td
(to)Tj
1.0417 0 Td
(rVes)Tj
2.0906 0 Td
(v)Tj
0.6874 0 Td
(5)Tj
0.7086 0 Td
(measured)Tj
4.1316 0 Td
(by)Tj
1.1976 0 Td
(ImmunoC)Tj
4.2308 0 Td
(AP)Tj
-21.1607 -1.4953 Td
(n\))Tj
1.1197 0 Td
(IgE-reactivit)Tj
4.996 0 Td
(y)Tj
0.6874 0 Td
(to)Tj
1.0417 0 Td
(rVes)Tj
2.0906 0 Td
(v)Tj
0.6874 0 Td
(1)Tj
0.7016 0 Td
(measured)Tj
4.1386 0 Td
(by)Tj
1.1976 0 Td
(ELISA)Tj
-16.6606 -1.5023 Td
(o\))Tj
1.0842 0 Td
(clinical)Tj
3.1039 0 Td
(severity)Tj
3.3024 0 Td
(in)Tj
1.0488 0 Td
(Mueller)Tj
3.3803 0 Td
(grade)Tj
2.4591 0 Td
(or)Tj
1.1126 0 Td
(large)Tj
2.1827 0 Td
(local)Tj
2.0977 0 Td
(reaction)Tj
-19.7717 -1.5024 Td
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