Care and observation of a germ-free neonate.
@article{Barnes1969CareAO, title={Care and observation of a germ-free neonate.}, author={Robert D. Barnes and Arnon Bentovim and S Hensman and Alina T Piesowicz}, journal={Archives of Disease in Childhood}, year={1969}, volume={44}, pages={211 - 217}, url={https://api.semanticscholar.org/CorpusID:4638651} }
The medical and nursing care of the infant during the period of investigation is described here, and it was postulated that the infant's immunological state would be relatively immature in the absence of foreign antigenic stimulation from the normal bacterial flora.
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21 References
A TECHNIQUE FOR THE DELIVERY OF A GERMFREE CHILD
- 1968
Medicine
The tent and each sleeve was fitted with a standard method successfully used for the Caesarean surgical rubber glove over a terminal rigid plastic delivery of a germfree infant, with ultimate introduction of the child widespread use of plastic film in the construction into the sterile maintenance isolator suitable for of isolation units.
Infectious complications of chemotherapy in a protected environment.
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Medicine, Environmental Science
The isolator system described below prevents the introduction of exogenous micro-organisms that can cause infection in malignant states but often the normal flora of the patient's skin and gastrointestinal tract as well.
Immunity Deficiency Syndromes
- 1967
Medicine, Biology
Work on germ-free animals shows that infection plays an important part in maturation of immune mechanisms, and defective mechanisms of resistance can be recognised only by the statistically insecure concept of increased incidence of infection.
Thymic Lymphocytophthisis with Terminal Aplastic Anaemia
- 1967
Medicine
Her development at the age of 18 months is normal in all fields except gross motor activity (which may be explained by her orthopeedic difficulties).
Patient protection in cancer chemotherapy.
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Medicine
In this small group of patients there was no evidence of infection with the more common pathogens, despite severe bone marrow depression and leukopenia induced by antitumor agents.
Flexible film apparatus for the rearing and use of germfree animals.
- 1957
Biology, Environmental Science
The investigations herein reported describe methods for sterile manipulations without the large investment previously required (Reyniers, 1946) with animals in the germfree or gnotobiotic state, that is, isolated, or in association with known organisms.
Use of germ-free mice for testing human isolation systems.
- 1968
Biology, Medicine
SUMMARY
Germ-free mice were introduced to test the efficiency and use of a human isolator designed to prevent the entry of viable bacteria. The mice remained free from bacterial contamination for…
A Germ-Free Isolator for Surgery in Mice
- 1968
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A description is given of an isolator available for experimental surgical procedures in mice and for the subsequent maintenance of these animals in the germ-free state.