Changes in energy metabolism during the suckling and weaning period in the newborn.

@article{Ferr1986ChangesIE,
  title={Changes in energy metabolism during the suckling and weaning period in the newborn.},
  author={Pascal Ferr{\'e} and Jean François Decaux and Tarik Issad and Jean R Girard},
  journal={Reproduction, nutrition, developpement},
  year={1986},
  volume={26 2B},
  pages={
          619-31
        },
  url={https://api.semanticscholar.org/CorpusID:4662748}
}
In most of the mammals, birth and weaning are two periods of nutritional transitions where the newborn adapts itself to the new nutritional environment by increasing its capacity to produce glucose de novo (gluconeogenesis) in order to satisfy its high glucose needs.

Integration of carbohydrate and lipid metabolism in skeletal muscle during postnatal development.

In the adult, muscle metabolism represents a large drain of energetic substrates and regulation of energetic substrate utilisation by muscle is of upmost importance for postnatal metabolic homeotasis.

Glucose Metabolism and Insulin Sensitivity During Suckling Period in Rats

In most mammals the mechanism contributing to the regulation of glucose metabolism does not seem to be fully developed during suckling, and either hormonal or nutritional changes occurring during the suckling-to-weaning transition are likely to contribute to the full development of the metabolic capacities of the pups.

Different effects of hyperlipidic diets in human lactation and adulthood: growth versus the development of obesity

In spite of human temporary adaptation to a high-fat (and sugars and protein) diet during lactation, the ability to thrive on this type of diet is lost irreversibly after weaning, and humans are unprepared for excess, and wholly adapted to survive scarcity.

Fish oil diet in pregnancy and lactation reduces pup weight and modifies newborn hepatic metabolic adaptations in rats

Maternal intake of high n-3 LCPUFA retards postnatal development, which could be the result of impaired ARA synthesis, and affects hepatic metabolic adaptations to extrauterine life.

Intestinal glucose absorption but not endogenous glucose production differs between colostrum- and formula-fed neonatal calves.

Metabolic and endocrine changes pointed to elevated amino acid degradation in group F, presumably to provide substrates to meet energy requirements and to compensate for impaired oral glucose uptake during the transition to extrauterine life.

Periodization of the early postnatal development in the rat with particular attention to the weaning period.

The early postnatal period is characterized by a great plasticity with critical windows in which any inadequate insult or intervention may be able to influence both positively and adversely postnatal

Enterohepatic Distribution of Carnitine in Developing Piglets: Relation to Glucagon and Insulin

The finding of a similar pattern in glucagon-to-insulin ratio suggests that both hormones may participate in the regulation of enterohepatic carnitine distribution in newborns.
...

Fatty acid oxidation and ketogenesis during development.

The nutritional and hormonal factors involved in changes in fatty acid oxidation during development are discussed and are attended by a progressive decrease in the ketogenic capacity of the liver at the time of weaning.

Fatty Acid Oxidation during Development

From the weight volume standpoint, the administration of fatty acids in parenteral nutrition can provide patients with significant nutritional increments and fatty acids are the preferred energy fuel of a number of tissues.

Changes in lipid synthesis in rat adipose tissue during development.

Weaning rats onto a high-fat diet showed decreases in glucose incorporation into fatty acids, insulin sensitivity, ATP citrate lyase activity and acetyl CoA carboxylase activity.

Role of the Insulin/Glucagon Ratio in the Changes of Hepatic Metabolism During Development of the Rat

The insulin/glucagon ratio was measured during the embryologic development of the rat and its changes were correlated with the variation in the diet and in liver metabolism, suggesting that glucagon plays a more important role during early life than during adult life.

Effects of medium-chain triglyceride feeding on glucose homeostasis in the newborn rat.

The data indicate that MCT feeding stimulates glucose production in the newborn rat, both by increasing the availability of gluconeogenic precursors and by a direct effect on hepatic gluconeogenesis.

Changes in hepatic lipigenesis during development of the rat.

Changes in the activities of ATP citrate lyase, ;malic' enzyme, glucose 6-phosphate dehydrogenase, pyruvate kinase, and fructose 1,6-diphosphatase have been measured in the livers of developing rats between late foetal life and maturity to discuss changes in alimentation and hormonal influences.

Changes in hepatic fatty acid degradation and blood lipid and ketone body content during development of the rat.

During the suckling period, when a constant high fat content diet is consumed, further marked changes in the parameters measured were observed which cannot be related to nutritional factors.

Development and regulation of ketogenesis in hepatocytes isolated from newborn rats.

Ketone-body production from oleate is increased 6-fold between 0 and 16 h after birth but this increase is related to an enhanced beta-oxidation rather than to a channeling of acetyl-CoA from the tricarboxylic acid cycle to ketone- body synthesis.

Digestion and absorption of milk triacylglycerols in 14-day-old suckling rats.

The fatty acid compositions of the major classes of lipid recovered from the contents of the stomach and small intestine, as well as, the chylomicron fraction of the serum of 14-day-old rats have
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